standard

ll 37

Overview

Evidence is being populated by Grok web search.

Sources

  1. Decoding LL-37: Structure and antimicrobial mechanisms ...
    “LL-37 effectively combats over 38 bacteria, 16 fungi, and 16 viruses through various mechanisms, including membrane rupture, targeting, and ...”
  2. LL-37 antimicrobial peptide: Molecular characterisation ...
    “LL-37 plays a multifaceted role in oral immunity by integrating antimicrobial, immunomodulatory, and tissue-regenerative functions.”
  3. Antimicrobial Peptides of the Cathelicidin Family: Focus on ...
    “LL-37-based analogs represent promising candidates for the development of next-generation antimicrobial and immunomodulatory therapies.”
  4. Significance of the LL-37 Peptide Delivered from Human ...
    “One approach to develop new treatments for patients with sepsis is to better understand the pleiotropic function of the human LL-37 peptide that ...”
  5. Human cathelicidin LL-37 rapidly disrupted colonic ...
    “LL-37 increases epithelial cell permeability by degrading TJ proteins occludin and claudin-2 through endocytosis and lysosomal degradation.”
  6. Human antimicrobial/host defense peptide LL-37 may ...
    “LL-37 may prevent the spread of a local infection through multiple mechanisms: an update”
  7. LL-37, the master antimicrobial peptide, its multifaceted ...
    “LL-37 has emerged as a significant player, demonstrating its multifaceted roles during bacterial, fungal, and viral infections, as well as exhibiting ...”
  8. Antimicrobial peptide LL-37 increases rhinovirus-induced ...
    “The human cathelicidin LL-37 is active against both bacteria and viruses , but it also shows immunomodulatory properties.”
  9. Study of cathelicidin (LL-37) immunoexpression in the skin ...
    “The present work aimed to study the immunoexpression of cathelicidin in the vitiligo patients' skin to elucidate its possible role in vitiligo pathogenesis.”
  10. LL-37 and citrullinated-LL-37 modulate IL-17A/F-mediated ...
    “Overall, our findings showed that LL-37 and citLL-37 can selectively suppress the abundance of IL-17A/F-mediated LCN-2, a protein that is ...”
  11. Cathelicidin LL-37 in periodontitis: current research progress and prospects
    “This review summarizes the expression and roles of LL-37 in periodontitis, providing new perspectives and insights into its pathogenesis and treatment.”
  12. Exploring the Role of Cathelicidin LL-37 and Ceragenins in Wound Healing
    “This work reviews literature describing the role of AMPs, particularly LL-37 and synthetic ceragenins, in wound healing.”
  13. Vitamin D-inducible antimicrobial peptide LL-37 binds SARS-CoV-2 Spike, ORF7a, and ORF8 proteins and inhibits viral replication
    “LL-37 disrupts key viral-host interactions by binding to Spike, ORF7a, and ORF8, thereby reducing SARS-CoV-2 infectivity.”
  14. LL-37 and bacterial DNA complexes in dental plaque
    “This review summarizes current knowledge of the molecular mechanisms and immunological consequences of LL-37-bacterial DNA interactions in dental plaque.”
  15. Vicenin-2 attenuates rosacea-like inflammation by targeting the IL-17RA/NF-κB pathway
    “Vicenin-2 alleviates LL-37-induced rosacea-like inflammation by regulating the IL-17RA/NF-κB pathway.”
  16. LL-37-derived peptide shows promising antimicrobial ...
    “In this study, we designed a series of antimicrobial peptides by fusing the two fragments of antimicrobial peptides Cathelicidin-BF (1-9) and LL-37 (17-29), and ...”
  17. CRISPR/Cas9-engineered Salmonella phage displaying ...
    “LL-37 -engineered bacteriophages demonstrated improved antibacterial activity and intracellular infection control against S. Typhimurium.”
  18. Structural determinants of glycosaminoglycan ...
    “The human antimicrobial peptide LL-37 exerts a dual role in cancer, promoting tumor progression in breast carcinoma by stimulating calcium influx and enhancing ...”
  19. Antimicrobial peptide WK-13-3D inhibits Japanese ...
    “In this study, we found that the synthetic LL-37 analogue peptide WK-13-3D has strong antiviral activity against JEV. Notably, pre-treatment or co-incubation ...”
  20. Salivary antimicrobial peptides histatin-5, beta defensins ...
    “Salivary antimicrobial peptides histatin-5, beta defensins, human neutrophilic peptides, LL-37 , and calprotectin in severe dental caries, with a focus on early ...”