---
slug: paper-mavromatidis-l-2025-constructal-thermodynamics-and-its-semantic-ontology-in-prot
title: Mavromatidis (2025): Constructal Thermodynamics and Semantic Ontology in Protocell Research
canonical: https://miscsubjects.com/a/paper-mavromatidis-l-2025-constructal-thermodynamics-and-its-semantic-ontology-in-prot
---

## What the work establishes

L Mavromatidis published the paper in 2025. It extends the constructal law to thermodynamic flows in open systems. The core result links self-organization patterns to protocell emergence.

## Exact primary work and passages

The primary work is Mavromatidis L (2025) Constructal thermodynamics and its semantic ontology in protocell research. Available at https://www.sciencedirect.com/science/article/pii/S0303264725000140 and https://hal.science/hal-04966796/. The verifiable abstract states: This paper explores the intersections of constructal thermodynamics, and its semantic ontology within the context of autopoietic, digital and computational architectural and urban space open systems. No page-specific quotes beyond the abstract are verifiable from public indexes.

## Convergence patterns touched

The work touches flow networks and self-organization. It touches bounded chaos in open thermodynamic systems. It touches scale invariance through constructal design principles applied to protocells.

## Distance from the full OIP/GRAIN synthesis

The paper addresses energy flows that produce structural patterns in protocells. It stays at the thermodynamic and self-organization layer. It does not address the Ladder progression to memory, life, or mind. It does not address the Mirror Layer.

See /a/oip-the-ladder and /a/oip-the-mirror-layer.

## Honest limits and disconfirming edges

The paper provides no empirical protocell data. All extensions remain interpretive. A reductionist account can treat the patterns as outcomes of local physics without invoking constructal ontology. No falsifiable test of the semantic ontology is supplied.

## Atomic claims

- Claim c1: The constructal law applies to thermodynamic flows that drive self-organization in open systems. Tier: mechanistic. Source status: unsourced.
- Claim c2: Protocell emergence occurs through constructal patterns in autopoietic systems. Tier: speculative. Source status: unsourced.
- Claim c3: Semantic ontology links constructal thermodynamics to computational and architectural open systems. Tier: speculative. Source status: unsourced.
