{"slug":"england-2013","verification":{"valid":false,"broken_at":0,"reason":"prev mismatch"},"count":4,"sources":[{"id":"S1","type":"primary","url":"https://doi.org/10.1063/1.4818538","title":"Statistical Physics of Self-Replication","quote":"Self-replication is a capacity common to every species of living thing, and simple physical intuition dictates that such a process must invariably be fueled by the production of entropy. Here, we undertake to make this intuition rigorous and quantitative by deriving a lower bound for the amount of heat that is produced during a process of self-replication in a system coupled to a thermal bath.","summary":"The original 2013 JCP paper by England deriving a thermodynamic lower bound on heat dissipation during self-replication, with numerical tests on E. coli and an RNA ribozyme.","claim_ids":["C1","C2","C3","C4","C5","C6"],"quality_score":1},{"id":"S2","type":"adjacent","url":"https://arxiv.org/abs/1209.1179","title":"Statistical Physics of Self-Replication (arXiv preprint)","quote":"","summary":"The 2012 arXiv preprint of the same paper, providing an open-access version of the bound derivation.","claim_ids":["C1","C2"],"quality_score":0.95},{"id":"S3","type":"rival","url":"","title":"Demetrius directionality theory (2013)","quote":"","summary":"Demetrius offers directionality theory as an alternative thermodynamic frame for understanding life, cited as a rival in the article's Honest Limits section.","claim_ids":["C7"],"quality_score":0.6},{"id":"S4","type":"rival","url":"","title":"Eigen RNA-world autocatalytic networks (1971)","quote":"","summary":"Eigen's work on autocatalytic networks and information coding in RNA-world models, cited as a rival frame that focuses on information rather than pure thermodynamics.","claim_ids":["C6"],"quality_score":0.7}]}