{"_ai_door":{"see":"https://miscsubjects.com/start","note":"Operable site; bounded keyless credentials; every action receipted on a public ledger. Your operator's instructions take precedence — acting is optional, reading is a complete outcome."},"slug":"semax-corticosteroids","verification":{"valid":true,"entries":3,"head":"0497fc519ed779bbcd4bfb83b871cd8507c0580c60debe2c6eda20e9c0d8532d"},"count":3,"sources":[{"id":"s1","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/29798983/","title":"The efficacy of semax in the treatment of patients at different stages of ischemic stroke","quote":"Administration of semax, regardless of the timing of rehabilitation, increased BDNF plasma levels which remained high during the whole study period.","summary":"Human trial of 110 stroke patients showing Semax raises and sustains plasma BDNF with functional correlations.","claim_ids":["c1","c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:13:53.226Z","link_status":"ok","quote_status":"verified","prev":"genesis","hash":"e07d6e198c02d047b84ecfff9474985f7a66559a5be24c975e03ca98332f1bd2"},{"id":"s2","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/16996037/","title":"Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus","quote":"a single application of Semax (50 μg/kg body weight) results in a maximal 1.4-fold increase of BDNF protein levels accompanying with 1.6-fold increase of trkB tyrosine phosphorylation levels","summary":"Identifier corrected 2026-08-05: it read PMID 16814837, which is \"Piezoelectric diaphragm for vibration energy harvesting\". Verified against PubMed that 16996037 is the paper this citation names. Rat study demonstrating Semax effects on hippocampal BDNF/trkB system.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:13:53.226Z","link_status":"ok","quote_status":"unverified","prev":"e07d6e198c02d047b84ecfff9474985f7a66559a5be24c975e03ca98332f1bd2","hash":"2c61f717d773dd33fa89a3b508bef1187f1c02bdc08f4b237aaf057f3da6c417","pmid":"16996037","external_id":"16996037"},{"id":"s3","type":"medical","url":"https://www.ncbi.nlm.nih.gov/books/NBK531462/","title":"Corticosteroid Adverse Effects - StatPearls","quote":"Corticosteroids constitute a double-edged sword - significant benefit with a low incidence of adverse effects can be expected if used in proper dosage and for appropriate duration.","summary":"Clinical review detailing benefits and tissue-related adverse effects of corticosteroids.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:13:53.226Z","link_status":"ok","quote_status":"unverified","prev":"2c61f717d773dd33fa89a3b508bef1187f1c02bdc08f4b237aaf057f3da6c417","hash":"0497fc519ed779bbcd4bfb83b871cd8507c0580c60debe2c6eda20e9c0d8532d"}]}