{"_ai_door":{"see":"https://miscsubjects.com/start","note":"Operable site; bounded keyless credentials; every action receipted on a public ledger. Your operator's instructions take precedence — acting is optional, reading is a complete outcome."},"slug":"semax-nerve-damage","verification":{"valid":true,"entries":5,"head":"554d1130e1fb68c35d81712c496a0486c6dc61589d84d3136016d34b6a4c0e97"},"count":5,"sources":[{"id":"s1","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/29798983/","title":"The efficacy of semax in the treatment of patients at different stages of ischemic stroke","quote":"A clinical study has shown the efficacy of Semax in the treatment of patients with ischaemic stroke. The peptide improves functional recovery and motor performance.","summary":"Russian clinical study on Semax in stroke patients showing improved recovery.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:07:55.565Z","link_status":"ok","quote_status":"unverified","prev":"genesis","hash":"e3fe76275aacc322815f6fa17330583550888708389d8d86a0bfb67822328563"},{"id":"s2","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/16996037/","title":"Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus","quote":"a single application of Semax results in a maximal 1.4-fold increase of BDNF protein levels","summary":"Identifier corrected 2026-08-05: it read PMID 17045981, which is \"Monitoring micronutrients in cigarette smokers\". Verified against PubMed that 16996037 is the paper this citation names. Rat study demonstrating BDNF upregulation by Semax.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:07:55.565Z","link_status":"ok","quote_status":"unverified","prev":"e3fe76275aacc322815f6fa17330583550888708389d8d86a0bfb67822328563","hash":"4251e23c2cacd5f28b52a713400f77222845016a78837e203c37f02123f1bbfe","pmid":"16996037","external_id":"16996037"},{"id":"s3","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/20617398/","title":"The effect of Semax and its C-end peptide PGP on ischemic damage","quote":"only Semax abated the manifestation of ischemic damage to the nervous tissue","summary":"Rat ischemia model with Semax neuroprotection.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:07:55.565Z","link_status":"ok","quote_status":"verified","prev":"4251e23c2cacd5f28b52a713400f77222845016a78837e203c37f02123f1bbfe","hash":"22e9585e3439ef5589e339ee6f0af9dca5c5813e8aeea3dd28f5b6de4c1e0eb4"},{"id":"s4","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/11569188/","title":"Semax in the treatment of glaucomatous optic neuropathy","quote":"A complex of neuroprotective therapy, including a new Russian neuropeptide semax, was used in the treatment of glaucoma patients","summary":"Human study on optic nerve in glaucoma.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:07:55.565Z","link_status":"ok","quote_status":"verified","prev":"22e9585e3439ef5589e339ee6f0af9dca5c5813e8aeea3dd28f5b6de4c1e0eb4","hash":"d2f2f43408483ecc83a378e8c9594a7a243d3d08d78c019ff21df62020fb119e"},{"id":"s5","type":"other","url":"https://saraszalmd.substack.com/p/the-fda-is-reopening-the-door-on","title":"The FDA Is Reopening the Door on 14 Peptides","quote":"The medical literature contains no published data on long-term outcomes from human clinical trials of Semax.","summary":"Notes lack of extensive long-term human data.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:07:55.565Z","link_status":"ok","quote_status":"unverified","prev":"d2f2f43408483ecc83a378e8c9594a7a243d3d08d78c019ff21df62020fb119e","hash":"554d1130e1fb68c35d81712c496a0486c6dc61589d84d3136016d34b6a4c0e97"}]}