{"_ai_door":{"see":"https://miscsubjects.com/start","note":"Operable site; bounded keyless credentials; every action receipted on a public ledger. Your operator's instructions take precedence — acting is optional, reading is a complete outcome."},"slug":"wolverine-stack-ara-290","verification":{"valid":true,"entries":24,"head":"1c38666d780e4c40f98651f00f53a4f642005e33966bbf7b9ef78551682e5d35"},"count":24,"sources":[{"id":"s1","url":"https://pubmed.ncbi.nlm.nih.gov/28475703/","title":"Culver DA et al. Cibinetide Improves Corneal Nerve Fiber Abundance in Patients With Sarcoidosis-Associated Small Nerve Fiber Loss and Neuropathic Pain. Phase 2b, NCT02039687. PMID 28475703","quote":"64 subjects, 16 per arm, 1, 4 or 8 mg subcutaneous daily for 28 days. Placebo-corrected change in corneal nerve fibre area: 109 µm² at 1 mg (not significant), 697 µm² at 4 mg (p = 0.012), 431 µm² at 8 mg (not significant). GAP-43+ regenerating skin fibres rose in the 4 mg arm, p = 0.035. Pain severity in the moderate-to-severe subgroup, p = 0.157.","_id":"w_z20pxaqf","_ts":"2026-08-04T19:18:24.795Z","type":"source","accessed_at":"2026-08-04T19:18:24.795Z","claim_ids":[],"prev":"genesis","hash":"e7c1ac3117f7d289546481084e44be89a72ada246837f6f3abdaabf0c5d5ba4f","plain":"The main human trial of ARA-290, and it is small: 64 people, 16 to a dose, 28 days. Only the middle dose moved the nerve-fibre measure and the higher one did not, which is not the shape of a real dose response. Pain did not separate."},{"id":"s2","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4365069/","title":"Brines M et al. ARA 290 in type 2 diabetes with painful neuropathy — randomised double-blind placebo-controlled trial, NTR3858, full text with pharmacokinetics and adverse events","quote":"49 enrolled, 48 analysed, 4 mg subcutaneous daily self-injected for 28 days with 56-day follow-up. HbA1c fell 0.16% at day 28 and 0.21% at day 56 versus 0.01% and +0.21% for placebo, p = 0.002. Corneal nerve fibre density rose 2.6 ± 1.0 fibres/mm² in the abnormal subgroup (n = 18, p = 0.02) against +0.7 for placebo.","_id":"w_odkk8zh8","_ts":"2026-08-04T19:18:24.932Z","type":"source","accessed_at":"2026-08-04T19:18:24.932Z","claim_ids":[],"prev":"e7c1ac3117f7d289546481084e44be89a72ada246837f6f3abdaabf0c5d5ba4f","hash":"4d71c539dc7ee609679a31cd53c301043cf842058b576fa72d62116b46f70ede","plain":"A second human trial, around fifty people with nerve pain from diabetes, four weeks of self-injection. The nerve-density gain came from a subgroup of eighteen carved out after the fact, and the firmest result was a blood-sugar change nobody was aiming at."},{"id":"s3","url":"https://clinicaltrials.gov/study/NCT02039687","title":"ClinicalTrials.gov NCT02039687 — Study of Efficacy of ARA 290 on Corneal Nerve Fiber Density and Neuropathic Symptoms of Subjects With Sarcoidosis. Completed","quote":"Phase 2, randomised, double-blind, placebo-controlled dose-ranging study of ARA 290 in sarcoidosis-associated small nerve fibre loss. Primary outcome: change in corneal nerve fibre area at day 28.","_id":"w_e64xt3k5","_ts":"2026-08-04T19:18:25.095Z","type":"source","accessed_at":"2026-08-04T19:18:25.095Z","claim_ids":[],"prev":"4d71c539dc7ee609679a31cd53c301043cf842058b576fa72d62116b46f70ede","hash":"35feb0d834ded8821dbc2f5517e34a60b0f6e647427b9fbd0949457aaefff9f4","plain":"The registry entry behind that sarcoidosis trial. It fixes what the study said it would measure before it ran, which is how you check the published paper did not move its own goalposts afterwards."},{"id":"s4","url":"https://pubmed.ncbi.nlm.nih.gov/22508732/","title":"Cohen SP et al. Epidural steroids, etanercept, or saline in subacute sciatica: a multicenter, randomized trial. Ann Intern Med 2012. PMID 22508732","quote":"Steroids beat saline by 1.26 points on the leg pain measure, which did not reach significance. Etanercept fared worse than steroids on functional capacity, by a margin that did.","_id":"w_z1jen5l5","_ts":"2026-08-04T19:18:25.240Z","type":"source","accessed_at":"2026-08-04T19:18:25.240Z","claim_ids":[],"prev":"35feb0d834ded8821dbc2f5517e34a60b0f6e647427b9fbd0949457aaefff9f4","hash":"5b248f0615085f0a2e4fc3f736aa7122ca2d243cab972b53f087d59b097036f2","plain":"Why the bar here is higher than it looks. In this trial steroid injections beat plain saline by an amount too small to be confident of — the established options for this problem do not clearly beat a needle full of nothing."},{"id":"s5","url":"https://pubmed.ncbi.nlm.nih.gov/42542926/","title":"Biçer O, Adanir O, Güleryüz Y, Balci EC. Effects of BPC-157 and TB-500 on Achilles tendon healing in rats: A histopathological and biomechanical study. Jt Dis Relat Surg, 23 July 2026. PMID 42542926","quote":"32 rats, Achilles transection and repair, four arms of eight, four weeks intraperitoneal: control, BPC-157 10 µg/kg/day, TB-500 60 µg/kg/day, or both. TB-500 alone raised maximum load to failure (p<0.05), Bonar score (p=0.016) and Movin score (p=0.017). The combination did not confer additional benefits compared to either agent alone.","_id":"w_ep5o267h","_ts":"2026-08-04T19:18:25.386Z","type":"source","accessed_at":"2026-08-04T19:18:25.386Z","claim_ids":[],"prev":"5b248f0615085f0a2e4fc3f736aa7122ca2d243cab972b53f087d59b097036f2","hash":"29dc106f0202e36088b0a2bc6c80a97ffe5a5f26b63796a8a8e01e17c0e78cd8","plain":"The only head-to-head test of BPC-157 and TB-500 together, run in 32 rats with a cut and repaired tendon, where combining them added nothing. Nothing in it touches discs, nerves, or the third compound on this page."},{"id":"s6","url":"https://x.com/MuroCrypto/status/2083184469956059529","title":"X — @MuroCrypto, 31 July 2026 — anecdotal, positive, herniated lumbar disc, ran both compounds","quote":"My lowest disc in the lower back is dried out, almost no fluid left, classic herniated disc. Flared up hard in March, could barely sit or stand without pain. Went on for 3 months with zero improvement. In June I ran BPC-157 and TB-500 for about 6 weeks. After 3-4 weeks it already felt better.","_id":"w_urq5czgf","_ts":"2026-08-04T19:18:25.526Z","type":"source","accessed_at":"2026-08-04T19:18:25.526Z","claim_ids":[],"prev":"29dc106f0202e36088b0a2bc6c80a97ffe5a5f26b63796a8a8e01e17c0e78cd8","hash":"798edfd4dca7fccf4a88df9a8fc3212d325a48fb377567f620929b991ed7e873","plain":"The closest thing here to a matched case: a dried-out lower disc, three months of no progress, then improvement three or four weeks into a six-week run of both compounds. Still one person, still no follow-up scan."},{"id":"s7","url":"https://www.reddit.com/r/Sciatica/comments/1rnicr5/pinched_sciatic_nerve/","title":"Reddit r/Sciatica — u/kunukxathletix, 7 March 2026 — anecdotal, positive, sciatic pain","quote":"I tried ever and eventually decided to try injectable BPC 157 and within a few weeks pain started to ease, well this could be random so I continued use after about 6-7 weeks sciatic pain was almost all the way gone","_id":"w_fwrufqlc","_ts":"2026-08-04T19:18:25.696Z","type":"source","accessed_at":"2026-08-04T19:18:25.696Z","claim_ids":[],"prev":"798edfd4dca7fccf4a88df9a8fc3212d325a48fb377567f620929b991ed7e873","hash":"efaf906fd92f029f2741a58434b24abaf1710d93ba4b0d0e188852d2bf2eab12","plain":"Sciatic pain nearly gone at six to seven weeks in one person, who flags unprompted that it might have been chance. BPC-157 only, no imaging, and long enough for the nerve to have settled on its own."},{"id":"s8","url":"https://x.com/drmarlonperalta/status/2062565899714925044","title":"X — @drmarlonperalta, 4 June 2026 — anecdotal, positive, ten years of low back pain from a herniated disc","quote":"I've suffered for 10+ years with lower back pain from a herniated disc. I would constantly reposition myself for relief while working. A 6-week cycle removed this distraction permanently.","_id":"w_zjktv1ck","_ts":"2026-08-04T19:18:25.852Z","type":"source","accessed_at":"2026-08-04T19:18:25.852Z","claim_ids":[],"prev":"efaf906fd92f029f2741a58434b24abaf1710d93ba4b0d0e188852d2bf2eab12","hash":"0fe317c19f1f02569a1c89fe9e82c2f82559895ba1fc7184f5a18b3f2a3a84a9","plain":"A decade of disc-related back pain reported as permanently resolved by a single six-week course — the largest claim on the page. No dose, no scan, no mention of what else changed across those weeks."},{"id":"s9","url":"https://x.com/AJA_Cortes/status/1794522474702336108","title":"X — @AJA_Cortes, 26 May 2024 — anecdotal, positive, L5-S1 flare, writer flags placebo himself","quote":"Decided to try to taking oral BPC157 at 2000mcg daily. Also got two deep tissue massages, and a chiro adjustment. 7 days later, pain free. Did the BPC157 help? Maybe, maybe not. Im always open to possibility of placebo.","_id":"w_5ukx2zgt","_ts":"2026-08-04T19:18:26.021Z","type":"source","accessed_at":"2026-08-04T19:18:26.021Z","claim_ids":[],"prev":"0fe317c19f1f02569a1c89fe9e82c2f82559895ba1fc7184f5a18b3f2a3a84a9","hash":"270188080870ba811474a2d3685ab95b9e292e4fda20f127b1b011f4f3ce367b","plain":"Three things inside one week — the oral form, two deep-tissue massages, a chiropractic adjustment — and then no pain. The writer refuses to give the compound the credit, which is the honest reading of a week like that."},{"id":"s10","url":"https://www.reddit.com/r/backpain/comments/1mu96us/hlab27_sacroiliitis_on_mri_vs_disc_obliteration/","title":"Reddit r/backpain — u/ImNotSchema, 19 August 2025 — anecdotal, no effect, ran both compounds","quote":"I also experimented with TB500 and BPC-157 peptides, but saw no improvement. The one thing that actually helped was Prednisone.","_id":"w_7l25c3et","_ts":"2026-08-04T19:18:26.183Z","type":"source","accessed_at":"2026-08-04T19:18:26.183Z","claim_ids":[],"prev":"270188080870ba811474a2d3685ab95b9e292e4fda20f127b1b011f4f3ce367b","hash":"ccd316586ec1303e18c8f304031783816e6fc2f65e2f75f9df7c70caaa610602","plain":"Both compounds tried on a back problem with nothing gained, while a steroid did the work. A rough comparison built into one report. No dose and no duration are given, so it cannot be weighed against the positive accounts."},{"id":"s11","url":"https://www.reddit.com/r/backpain/comments/1ccysh4/chronic_onesided_thoracic_pain/","title":"Reddit r/backpain — u/Dizzy-Breakfast-9405, 25 April 2024 — anecdotal, no effect after a month","quote":"I even tried peptides (BPC-157) for a month, no results.","_id":"w_o7zb1nkh","_ts":"2026-08-04T19:18:26.407Z","type":"source","accessed_at":"2026-08-04T19:18:26.407Z","claim_ids":[],"prev":"ccd316586ec1303e18c8f304031783816e6fc2f65e2f75f9df7c70caaa610602","hash":"aaf124740bf0586e55a79ea6ad0dd300c1cdd306875c7032e774f7bc0b3358e0","plain":"A month of BPC-157 against one-sided upper back pain, no result, mentioned in passing. Thin — no dose, no route — but a negative at a duration by which most accounts claim something should have happened."},{"id":"s12","url":"https://www.reddit.com/r/backpain/comments/1fi50ar/bpc_157_and_tb_500_for_herniated_disc/","title":"Reddit r/backpain — u/Miserable_Fan1984, 16 September 2024 — anecdotal, got worse, herniated disc, ran both compounds","quote":"I started taking bpc 157 and tb 500 and 500mcg a day to help with healing but I have started to feel worse and have pain going down my leg again.","_id":"w_bxksimvy","_ts":"2026-08-04T19:18:26.561Z","type":"source","accessed_at":"2026-08-04T19:18:26.561Z","claim_ids":[],"prev":"aaf124740bf0586e55a79ea6ad0dd300c1cdd306875c7032e774f7bc0b3358e0","hash":"719e140ed0baf5ec101cce5e11729977e5cf00bcc37020c9068749ad323a4860","plain":"Both compounds at 500mcg a day for a disc, and the leg pain returned worse than before. No one can separate the compounds from the disc's own course, which is the ceiling on every report of this kind here."},{"id":"s13","url":"https://x.com/NewsDeskOne/status/2077929820760019113","title":"X — @NewsDeskOne, 17 July 2026 — anecdotal, positive, ARA-290 for nerve symptoms in the feet","quote":"Did a run of ara 290, seemed to make a difference in neuropathy and sensitivity in my feet. This was after a couple months of bpc and 500","_id":"w_fq4pi400","_ts":"2026-08-04T19:18:26.712Z","type":"source","accessed_at":"2026-08-04T19:18:26.712Z","claim_ids":[],"prev":"719e140ed0baf5ec101cce5e11729977e5cf00bcc37020c9068749ad323a4860","hash":"cc8bf50af5e15cbaa53716ba33071d3b43006edb79fd22d02e045efc6889881d","plain":"The only account on this page of anyone running the third compound after the other two, and it concerns nerve symptoms in the feet rather than a nerve under pressure in the back. Sequential, not combined, and judged on feel alone."},{"id":"s14","url":"https://x.com/vedichi_/status/2077787145238913472","title":"X — @vedichi_, 16 July 2026 — anecdotal, skeptical, names the read-across problem directly","quote":"most of the ARA-290 data is small-fiber neuropathy, not compression. does the repair signalling do anything while the tunnel is still squeezing the nerve?","_id":"w_4wuabsyj","_ts":"2026-08-04T19:18:26.878Z","type":"source","accessed_at":"2026-08-04T19:18:26.878Z","claim_ids":[],"prev":"cc8bf50af5e15cbaa53716ba33071d3b43006edb79fd22d02e045efc6889881d","hash":"1d5f383bd30ac36c910ace8adb964036dfe906e9638d97861195d704528f8810","plain":"Here because it names the weakest link better than the studies do: the ARA-290 evidence comes from nerves damaged by disease, not nerves being squeezed. Nothing else on this page answers that objection."},{"id":"s15","url":"https://www.nationwidepeptides.com/products/ara-290-cibinetide-peptide/","title":"Nationwide Peptides — ARA-290 (cibinetide), BPC-157 and TB-500 research-chemical listings, prices read 4 August 2026","quote":"ARA-290 (Cibinetide) Peptide $43.00. BPC-157 Peptide price range: $42.00 through $63.00. TB-500 Peptide (TB4) price range: $38.00 through $61.00. For Research Use Only. Not for human use.","_id":"w_128kgmjo","_ts":"2026-08-04T19:18:27.086Z","type":"source","accessed_at":"2026-08-04T19:18:27.086Z","claim_ids":[],"prev":"1d5f383bd30ac36c910ace8adb964036dfe906e9638d97861195d704528f8810","hash":"6f06a5349984cc1ed9af7fb65811960b4e74fb65c593e494bc6366da8e963716","plain":"One seller's current list prices for all three compounds, which is where the cost arithmetic on this page comes from. The same listing carries the seller's own statement that none of it is meant to go into a person."},{"id":"s16","url":"https://luxepeptides.is/ara-290/","title":"Luxe Peptides — ARA-290 peptide listing, prices read 4 August 2026","quote":"ARA-290 Peptide — 10 mg at $50.00, 16 mg at $70.00. Research use only.","_id":"w_tblk1fxc","_ts":"2026-08-04T19:18:27.244Z","type":"source","accessed_at":"2026-08-04T19:18:27.244Z","claim_ids":[],"prev":"6f06a5349984cc1ed9af7fb65811960b4e74fb65c593e494bc6366da8e963716","hash":"1a54fbbaebf65a91598a3b9c97a879106a9bc140c141d46d404b1218a9c731ad","plain":"A second seller's ARA-290 prices, kept so the cost figures do not rest on a single shop. Same research-use-only labelling, broadly the same money for the same amount."},{"id":"s17","url":"https://www.fda.gov/drugs/human-drug-compounding/certain-bulk-drug-substances-use-compounding-may-present-significant-safety-risks","title":"FDA — Certain Bulk Drug Substances for Use in Compounding That May Present Significant Safety Risks, current as of 22 April 2026","quote":"Bulk drug substances nominated but withdrawn. This list of bulk drug substances previously in category 2 of the interim policies were withdrawn by the nominators. Thymosin beta-4, fragment (LKKTETQ), also known as TB-500: FDA has not identified any human exposure data drug products containing Thymosin Beta-4, Fragment. Cibinetide and ARA-290 appear nowhere on this page.","_id":"w_nw8mu388","_ts":"2026-08-04T19:18:27.400Z","type":"source","accessed_at":"2026-08-04T19:18:27.400Z","claim_ids":[],"prev":"1a54fbbaebf65a91598a3b9c97a879106a9bc140c141d46d404b1218a9c731ad","hash":"cec8b1b9b360f879a004568911def6808bd1f32b52ef8740192099aa378e9141","plain":"Two things at once: the agency found no human exposure data for TB-500, and cibinetide appears nowhere on the page. Absence from a risk list is not clearance — it means nobody put it forward for compounding at all."},{"id":"s18","url":"https://www.fda.gov/advisory-committees/advisory-committee-calendar/july-23-24-2026-meeting-pharmacy-compounding-advisory-committee-07232026","title":"FDA — 23-24 July 2026 meeting of the Pharmacy Compounding Advisory Committee","quote":"Committee considered whether BPC-157, KPV and TB-500 should be placed on the 503A bulks list. The vote is advisory; FDA is not bound by it and no rulemaking has completed.","_id":"w_iaxj5vbm","_ts":"2026-08-04T19:18:27.556Z","type":"source","accessed_at":"2026-08-04T19:18:27.556Z","claim_ids":[],"prev":"cec8b1b9b360f879a004568911def6808bd1f32b52ef8740192099aa378e9141","hash":"05e8b89d58fad32942135a3ca47d08d1bdf5c6c6198e71d1fb92bfa67bb8849d","plain":"The meeting record, useful mainly for what it withholds. The committee's vote advises and does not bind, and no rulemaking has finished, so nothing about what may lawfully be compounded has actually changed."},{"id":"s19","url":"https://www.wada-ama.org/sites/default/files/2025-09/2026list_en_final_clean_september_2025.pdf","title":"World Anti-Doping Code International Standard — Prohibited List 2026, effective 1 January 2026","quote":"S2.3 Growth Factors and Growth Factor Modulators: Thymosin-ß4 and its derivatives e.g. TB-500. S0 Non-Approved Substances: any pharmacological substance with no current approval by any governmental regulatory health authority for human therapeutic use. Prohibited at all times.","_id":"w_sjpd3ktu","_ts":"2026-08-04T19:18:27.700Z","type":"source","accessed_at":"2026-08-04T19:18:27.700Z","claim_ids":[],"prev":"05e8b89d58fad32942135a3ca47d08d1bdf5c6c6198e71d1fb92bfa67bb8849d","hash":"bd8985579bba951e1e5bedd7e682c37223a2fc357019830cf528892322892e1a","plain":"For anyone subject to testing this closes the question. TB-500 is named directly, and the rest fall under the blanket clause covering substances no health authority has approved. In force at all times, not only on competition day."},{"id":"s20","url":"https://clinicaltrials.gov/study/NCT07437547","title":"NCT07437547 — A Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial of Pentadecapeptide BPC 157 for Accelerated Repair of Acute Grade II Hamstring Strain Confirmed by MRI. Hudson Biotech. Recruiting, started 2 February 2026","quote":"120 participants planned. Subcutaneous injection once daily for 14 days versus placebo. Primary outcomes: time to return to unrestricted sport participation at 8 weeks, and change from baseline to day 14 in MRI-assessed hamstring injury volume by blinded central radiology review.","_id":"w_nf67i8u8","_ts":"2026-08-04T19:18:27.844Z","type":"source","accessed_at":"2026-08-04T19:18:27.844Z","claim_ids":[],"prev":"bd8985579bba951e1e5bedd7e682c37223a2fc357019830cf528892322892e1a","hash":"17f5eef8fb243c07e58658c897b30d427be8467f263f90195ba2f05162f139dd","plain":"The first placebo-controlled human test of BPC-157 is underway and has not reported. It studies a torn hamstring in isolation — not a disc, not a compressed nerve, and not in company with the other two compounds."},{"id":"s21","url":"https://pubmed.ncbi.nlm.nih.gov/41966639/","title":"Safety and Efficacy of Approved and Unapproved Peptide Therapies for Musculoskeletal Injuries and Athletic Performance. Sports Med, 12 April 2026. PMID 41966639","quote":"Independent 2026 review of the peptide musculoskeletal literature, covering BPC-157 and thymosin beta-4 products.","_id":"w_4kzzhg35","_ts":"2026-08-04T19:18:28.008Z","type":"source","accessed_at":"2026-08-04T19:18:28.008Z","claim_ids":[],"prev":"17f5eef8fb243c07e58658c897b30d427be8467f263f90195ba2f05162f139dd","hash":"e073cb454b965c1891f9525270a76028f6c173e3dec4603500afa4bb4d421ec7","plain":"A 2026 survey of the published musculoskeletal peptide literature, covering the two compounds in the base pair. It sits here as an outside check on the primary papers; the line quoted gives its scope, not its verdict."},{"id":"s22","url":"https://pubmed.ncbi.nlm.nih.gov/41490200/","title":"Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions. J Am Acad Orthop Surg Glob Res Rev, 1 January 2026. PMID 41490200","quote":"Independent 2026 orthopaedic review of therapeutic peptides, their applications and the state of the evidence.","_id":"w_1cl98fhr","_ts":"2026-08-04T19:18:28.155Z","type":"source","accessed_at":"2026-08-04T19:18:28.155Z","claim_ids":[],"prev":"e073cb454b965c1891f9525270a76028f6c173e3dec4603500afa4bb4d421ec7","hash":"f0f525fdf54cd1dc9a95c0e34be3a2d11655ca8fd4e3b623176921b96a195545","plain":"A second 2026 review, from the orthopaedic literature, on where therapeutic peptides actually stand. Two independent surveys months apart are on the page so it does not rest on one group's reading of the field."},{"id":"s23","url":"https://pubmed.ncbi.nlm.nih.gov/37559207/","title":"Incidence of Spontaneous Resorption of Lumbar Disc Herniation: A Meta-analysis. Clin Spine Surg, 2024. PMID 37559207","quote":"31 studies, 2,233 conservatively treated patients. Overall spontaneous resorption rate 70.39%: 87.77% for sequestration, 66.91% for extrusion, 37.53% for protrusion, 13.33% for bulging.","_id":"w_7h14hzc8","_ts":"2026-08-04T19:18:28.324Z","type":"source","accessed_at":"2026-08-04T19:18:28.324Z","claim_ids":[],"prev":"f0f525fdf54cd1dc9a95c0e34be3a2d11655ca8fd4e3b623176921b96a195545","hash":"41705da420faf1e9228f0eebebe5c3f967c30ac13f0f98ff8f9c6adbcb21eda4","plain":"The number that makes every disc anecdote hard to read: across 31 studies and 2,233 people managed without surgery, most herniations shrank on their own. Anything taken during those months will look like it worked."},{"id":"s24","url":"https://pubmed.ncbi.nlm.nih.gov/24165696/","title":"Randomized, double-blind, placebo-controlled trial of transforaminal epidural etanercept for symptomatic lumbar disc herniation. PMID 24165696","quote":"49 patients across three doses. Separation from placebo appeared only at the lowest dose, 0.5 mg; the 2.5 mg and 12.5 mg arms did not separate, at a significance threshold of P < 0.1.","_id":"w_fe60t5ka","_ts":"2026-08-04T19:18:28.484Z","type":"source","accessed_at":"2026-08-04T19:18:28.484Z","claim_ids":[],"prev":"41705da420faf1e9228f0eebebe5c3f967c30ac13f0f98ff8f9c6adbcb21eda4","hash":"1c38666d780e4c40f98651f00f53a4f642005e33966bbf7b9ef78551682e5d35","plain":"A cautionary result from a neighbouring drug: of three doses, only the smallest beat placebo, and only against a loose significance bar. When the middle and top doses do nothing, the finding at the bottom is likely noise."}]}