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"excerpt": " Ophirex | Pioneering a new approach for treating snakebite Skip to content About Science Pipeline Varespladib for Human Use Varespladib for Animal Use Snakebite Burden Human Health Animal Health News Contact About Science Pipeline Varespladib for Human Use Varespladib for Animal Use Snakebite Burden Human Health Animal Health News Contact Pioneering a new approach for treating snakebite Pioneering a new approach for treating snakebite Pioneering a new approach for treating snakebite Pioneering a new approach for treating snakebite Learn More “ Nothing has really changed in how snakebites have been treated for over 100 years. Our goal is to change that now.” -Jeremy Gowler, CEO & Board Director Learn More Snakebite burden Development progress Adapted from Figure 6 in: Escalante T, Ortiz N, Rucavado A, Sanchez EF, Richardson M, Fox JW, et al. (2011) Role of Collagens and Perlecan in Microvascular Stability: Exploring the Mechanism of Capillary Vessel Damage by Snake Venom Metalloproteinases. PLoS ONE 6(12): e28017. https://doi.org/10.1371/journal.pone.0028017. Licensed under CC BY 4.0 ( https://creativecommons.org/licenses/by/4.0/ ). Arrows removed for clarity and image quality and color is adjusted and enhanced using AI Learn More Ophirex’s lead candidate is varespladib, a small-molecule inhibitor of snake venom secretory phospholipase A2 (sPLA2), a class of toxins present in the venom of 95% of snake species. An oral treatment for snakebite could reduce the time to treatment from hours to minutes. Learn More © 2026 Ophirex, Inc. All rights reserved. Privacy Policy Terms of Use Expanded Access Policy About Science Pipeline Varespladib for Human Use Varespladib for Animal Use Snakebite Burden Human Health Animal Health News Contact (opens in a new tab) About Science Pipeline Varespladib for Human Use Varespladib for Animal Use Snakebite Burden Human Health Animal Health News Contact © 2025 Ophirex. All rights reserved. Privacy Policy Terms of Use Expanded Access Policy ",
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