Kindt, Soeter & Vervliet (2009) — propranolol and human fear memory reconsolidation
Citation: Kindt M, Soeter M, Vervliet B. "Beyond extinction: erasing human fear responses and preventing the return of fear." Nature Neuroscience 12(3):256–258 (2009).
Identifiers: PMID 19219038; DOI 10.1038/nn.2271.
Retrieved from: https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=19219038&rettype=abstract&retmode=xml (record also at https://pubmed.ncbi.nlm.nih.gov/19219038/)
"Animal studies have shown that fear memories can change when recalled, a process referred to as reconsolidation. We found that oral administration of the beta-adrenergic receptor antagonist propranolol before memory reactivation in humans erased the behavioral expression of the fear memory 24 h later and prevented the return of fear. …" [The abstract's remaining sentence states that disrupting fear-memory reconsolidation opens new avenues for long-term treatment of patients with emotional disorders.]
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